2. Signaling Pathways
  3. Vitamin D Related/Nuclear Receptor
  4. Progesterone Receptor
  5. Progesterone Receptor Modulator

Progesterone Receptor Modulator

Progesterone Receptor Modulators (8):

Cat. No. Product Name Effect Purity
  • HY-119433
    Asoprisnil
    		Modulator 98.30%
    Asoprisnil (J867), a selective progesterone receptor modulator, exhibits mixed progesterone agonist and antagonist effects on various progesterone targeted tissues in animal and human.
  • HY-14959
    Ulipristal
    		Modulator ≥98.0%
    Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system.
  • HY-16775
    Vilaprisan
    		Modulator 99.75%
    Vilaprisan is a selective progesterone receptor modulator (SPRM), which targets progesterone receptors. Vilaprisan can inhibit cell proliferation and stimulate apoptosis. Vilaprisan has oral efficacy and anti-proliferative activity against uterine leiomyoma (UF).
  • HY-16483
    Telapristone acetate
    		Modulator
    Telapristone acetate (CDB-4124) is a potent progesterone receptor (PR) modulator. Telapristone acetate inhibits the proliferation of ovarian cancer cells by inducing cell cycle arrest and apoptosis. Telapristone effectively inhibits the occurrence and development of spontaneous and chemically induced mammary tumors in rats. Telapristone acetate can be used for breast and ovarian cancer research[1][2].
  • HY-W753635
    EC 313
    		Modulator
    EC 313 is a novel selective progesterone receptor modulator. EC 313 can dose dependently reduce the weight of fibroids. EC 313 can reduce the expression of ER and PR. EC 313 can be used for the study of uterine fibroids.
  • HY-106140A
    Asoprisnil ecamate
    		Modulator
    Asoprisnil ecamate (J 956) is an orally active antiprogestin, and can be used for contraception.
  • HY-105177
    ORG 33628
    		Modulator
    ORG 33628 is a potent and selective progesterone receptor modulator. ORG 33628 shows anti-progestational and anti-glucocorticoid activity. ORG 33628 shows ovulation-inhibitory activity. ORG 33628 has the potential for the research of breast and endometrium.
  • HY-14959S
    Ulipristal-d3
    		Modulator
    Ulipristal-d3 (CDB-3236-d3) is deuterium labeled Ulipristal. Ulipristal (CDB 3236) is a selective progesterone receptor modulator (SPRM). Ulipristal binds to the progesteron receptor, thereby inhibiting PR-mediated gene expression, and interfering with progesterone activity in the reproductive system.